Description

4-((3-(Ethoxycarbonyl)-7-(Trifluoromethyl)Quinolin-4-Yl)Amino)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-benzoic acid hybrid structure. This compound is critical for the synthesis of novel drug candidates, particularly in the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry and process development for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under GMP conditions.
• Oncology Drug Candidates: Integral to the development of targeted small-molecule inhibitors, leveraging the trifluoromethyl-quinoline pharmacophore.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A substrate for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	4-((3-(Ethoxycarbonyl)-7-(Trifluoromethyl)Quinolin-4-Yl)Amino)Benzoic Acid
CAS No.	793627-43-7
Molecular Formula	C20H15F3N2O4
Molecular Weight	404.34 g/mol
Synonyms	4-[(3-Ethoxycarbonyl-7-trifluoromethyl-4-quinolyl)amino]benzoic acid; 4-((3-(Ethoxycarbonyl)-7-(trifluoromethyl)-4-quinolinyl)amino)benzoic acid; Benzoic acid, 4-[[3-(ethoxycarbonyl)-7-(trifluoromethyl)-4-quinolinyl]amino]-; 4-[[3-(Ethoxycarbonyl)-7-(trifluoromethyl)-4-quinolyl]amino]benzoic acid; 4-[(3-Ethoxycarbonyl-7-trifluoromethylquinolin-4-yl)amino]benzoic acid; CAS 793627-43-7
EINECS	Contact for details

Quality Control

Our production of 4-((3-(Ethoxycarbonyl)-7-(Trifluoromethyl)Quinolin-4-Yl)Amino)Benzoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.