Description

2-Propanol,1-(Aminooxy)-3-(4-Methylphenoxy)-,(2R)-(9Ci) is a specialized chiral building block featuring both aminooxy and aryloxy functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Ligand Synthesis: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Bioconjugation Chemistry: The aminooxy group enables efficient oxime ligation for bioconjugation applications in antibody-drug conjugate (ADC) development and protein labeling.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Polymer Modification: Employed to introduce functional handles into polymer backbones for creating advanced materials with tailored properties.
• Chemical Biology Probes: Useful in synthesizing molecular probes for studying biological pathways and enzyme activity.

Basic Information

Product Name	2-Propanol,1-(Aminooxy)-3-(4-Methylphenoxy)-,(2R)-(9Ci)
CAS No.	792177-83-4
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(2R)-1-(Aminooxy)-3-(4-methylphenoxy)propan-2-ol; (R)-1-(Aminooxy)-3-(p-tolyloxy)propan-2-ol; 1-Aminooxy-3-(4-methylphenoxy)-2-propanol, (2R)-; 2-Propanol, 1-(aminooxy)-3-(4-methylphenoxy)-, (2R)-; (R)-O-(2-Hydroxy-3-(4-methylphenoxy)propyl)hydroxylamine; p-Tolyloxypropanolamine O-ether, (R)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.