Description

8-Bromo-6-quinolinecarboxylic acid is a versatile brominated quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its bifunctional structure, combining a reactive bromine substituent with a carboxylic acid group, enabling diverse derivatization pathways for constructing complex molecular architectures. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate in the production of organic semiconductors, dyes, and photoactive materials due to its conjugated aromatic system.
• Chemical Biology: Useful for synthesizing molecular probes and tags for studying biological processes.
• Academic & Industrial R&D: Employed in method development and exploratory synthesis across multiple chemistry disciplines.

Basic Information

Product Name	8-Bromo-6-quinolinecarboxylic Acid
CAS No.	791632-21-8
Molecular Formula	C10H6BrNO2
Molecular Weight	252.07 g/mol
Synonyms	8-Bromo-6-quinolinecarboxylic acid; 6-Quinolinecarboxylic acid, 8-bromo-; 8-Bromoquinoline-6-carboxylic acid; 8-Bromo-6-quinolincarboxylic acid; 791632-21-8; 8-Bromo-quinoline-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-quinolinecarboxylic acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.