Description

(1R)-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthalene CAS NO 791616-66-5 is a chiral, substituted binaphthyl derivative that serves as a sophisticated intermediate in asymmetric synthesis. This compound is valued for its rigid, three-dimensional structure, which makes it an excellent precursor for constructing chiral ligands and catalysts. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of enantioselective processes and advanced organic materials.

Application

• As a key chiral building block for the synthesis of axially chiral ligands, such as BINOL and BINAP derivatives.
• Precursor in the preparation of organocatalysts and transition metal catalysts for asymmetric hydrogenation and C-C bond formation.
• Intermediate in pharmaceutical research for constructing enantiomerically pure active pharmaceutical ingredients (APIs).
• Used in material science for developing chiral stationary phases (CSPs) for chromatographic separation.
• Starting material for advanced polymer and supramolecular chemistry applications requiring defined chirality.
• Research chemical for studying chiral recognition and molecular self-assembly phenomena.

Basic Information

Product Name	(1R)-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthalene
CAS No.	791616-66-5
Molecular Formula	C₂₄H₃₀O₄
Molecular Weight	382.50 g/mol
Synonyms	(R)-H8-BINOL-2,2'-dimethyl ether; (R)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol 2,2'-dimethyl ether; (1R)-2,2'-Bis(methoxymethoxy)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene; (R)-H8-BINOL(MOM)₂; Octahydro-BINOL dimethyl ether derivative; Chiral binaphthyl ether; (R)-H8-BINOL-2,2'-bis(methyl ether)
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.