Description

(R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthalene is a high-value, chiral binaphthyl derivative that serves as a critical advanced intermediate in asymmetric synthesis. Its core value lies in its rigid, three-dimensional structure, which is essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise stereochemical control is paramount.

Application

• Asymmetric Ligand Precursor: Key building block for synthesizing chiral phosphine, phosphoramidite, and N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Pharmaceutical Intermediate: Employed in the research and development of enantiomerically pure drugs, particularly in constructing axially chiral backbones for kinase inhibitors and other targeted therapies.
• Organocatalyst Synthesis: Serves as a foundational scaffold for developing novel Brønsted acid and phase-transfer catalysts for fine chemical production.
• Material Science Research: Used in the creation of chiral polymers, liquid crystals, and molecular recognition systems for sensor technology.
• Agrochemical Development: Intermediate for the synthesis of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Academic & Process Chemistry: A valuable tool for methodological studies in enantioselective C-C and C-X bond-forming reactions in university and industrial R&D labs.

Basic Information

Product Name	(R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthalene
CAS No.	791616-64-3
Molecular Formula	C26H30Br2O4
Molecular Weight	566.33 g/mol
Synonyms	(R)-3,3'-Dibromo-2,2'-bis(methoxymethoxy)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene; (R)-H8-BINOL-3,3'-dibromide-2,2'-bis(MOM ether); (R)-3,3'-Dibromo-2,2'-di(methoxymethoxy)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diyl bis(methoxymethyl) ether; (R)-H8-BINOL-3,3'-dibromo-2,2'-bis-MOM; (R)-3,3'-Dibromo-2,2'-bis(methoxymethoxy)-octahydrobinaphthyl
EINECS	Contact for details

Quality Control

Our (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.