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R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol CAS NO 791616-58-5
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CAS No.:791616-58-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative, prized for its role as a sophisticated ligand and building block in asymmetric synthesis. Its core value lies in its ability to induce high enantioselectivity in catalytic reactions, which is critical for producing single-isomer pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.
Application
- As a chiral ligand for transition metal catalysts in asymmetric hydrogenation, coupling, and oxidation reactions.
- Key intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
- Building block for constructing chiral polymers and advanced organic materials with specific optical properties.
- Utilized in the development of chiral stationary phases for analytical and preparative chromatography.
- Precursor for novel organocatalysts used in green and sustainable chemistry applications.
- Research chemical for academic and industrial studies in stereoselective synthesis and catalysis.
Basic Information
| Product Name | R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol |
| CAS No. | 791616-58-5 |
| Molecular Formula | C34H20F6O2 |
| Molecular Weight | 574.52 g/mol |
| Synonyms | (R)-3,3'-Bis[4-(trifluoromethyl)phenyl]-1,1'-binaphthalene-2,2'-diol; (R)-3,3'-Bis(4-trifluoromethylphenyl)-BINOL; (R)-3,3'-Bis(4-(trifluoromethyl)phenyl)-2,2'-dihydroxy-1,1'-binaphthyl; R-3,3'-(4-Trifluoromethylphenyl)-BINOL; (R)-3,3'-Di(4-trifluoromethylphenyl)-BINOL; R-BINOL-CF3 Derivative; Chiral BINOL Ligand; Asymmetric Synthesis Ligand |
| EINECS | Contact for details |
Quality Control
Our R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and IR for structural confirmation, to ensure high chemical and optical purity. Certificates of Analysis (COA) with full specification data are provided to guarantee consistency and reliability for your critical synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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