Description

6-(Trifluoromethyl)Quinolin-2-Amine is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly for kinase inhibitors, anti-cancer agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the properties of the quinoline scaffold.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, OLED materials, and liquid crystals.
• Chemical Synthesis: Acts as a versatile building block for constructing more complex heterocyclic compounds in medicinal and process chemistry.
• Bioconjugation & Probe Development: Utilized in the design of fluorescent probes, biomarkers, and other diagnostic tools due to its modifiable amine group.

Basic Information

Product Name	6-(Trifluoromethyl)Quinolin-2-Amine
CAS No.	791595-93-2
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)quinoline; 6-(Trifluoromethyl)-2-quinolinamine; 2-Quinolinamine, 6-(trifluoromethyl)-; Quinolin-2-amine, 6-(trifluoromethyl)-; 791595-93-2; 6-Trifluoromethylquinolin-2-ylamine
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Quinolin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.