Description

3,5-Difluorophenylthiourea is a specialized fluorinated thiourea derivative, a high-value intermediate in advanced organic synthesis. This compound is particularly valued for its role as a key building block in the development of pharmaceuticals and agrochemicals, where its difluorophenyl moiety can significantly influence biological activity and metabolic stability. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorine into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating thiourea-based organocatalysts or metal-complexing ligands in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive in the creation of specialized polymers with unique electronic or surface properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.

Basic Information

Product Name	3,5-Difluorophenylthiourea
CAS No.	791594-33-7
Molecular Formula	C7H6F2N2S
Molecular Weight	188.20 g/mol
Synonyms	1-(3,5-Difluorophenyl)thiourea; N-(3,5-Difluorophenyl)thiourea; Thiourea, N-(3,5-difluorophenyl)-; 3,5-Difluorophenyl-thiourea; (3,5-Difluorophenyl)thiourea; 791594-33-7; 3,5-Difluorophenyl thiocarbamide
EINECS	Contact for details

Quality Control

Our 3,5-Difluorophenylthiourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.