Description

(2S)-2-[[[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]-N-benzyl-N,3,3-trimethylbutanamide is a sophisticated chiral organic compound featuring a salicylaldimine-thiourea hybrid structure, designed for high-performance applications. Its precise stereochemistry and multi-functional design make it a valuable ligand or catalyst precursor in asymmetric synthesis and metal complexation. This advanced intermediate is critical for R&D and production in the pharmaceutical, agrochemical, and fine chemical sectors, where enantioselective control is paramount.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor for enantioselective organic transformations, including hydrogenation, addition, and coupling reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Metal Complexation & Chelation: Acts as a selective chelating agent for transition metals in analytical chemistry or material science.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, flavors, and fragrances where chiral purity is essential.
• Academic & Industrial R&D: A valuable tool for chemists exploring new catalytic systems and chiral induction methodologies.

Basic Information

Product Name	(2S)-2-[[[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]-N-benzyl-N,3,3-trimethylbutanamide
CAS No.	479423-24-0
Molecular Formula	C37H56N4O2S
Molecular Weight	620.93 g/mol
Synonyms	(2S)-2-[[[[(1R,2R)-2-[[[3,5-Bis(1,1-dimethylethyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide; Salicylaldimine-Thiourea Hybrid Ligand; Chiral Salen-Thiourea Derivative; N-Benzyl-N,3,3-trimethyl-2-[[[[(1R,2R)-2-[[[3,5-di-tert-butyl-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]butanamide (2S)-; 479423-24-0; Chiral Bifunctional Organocatalyst Precursor
EINECS	Contact for details

Quality Control

Our production of this advanced chiral compound adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profile is provided with each shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic and/or light-sensitive; handle under an inert atmosphere when appropriate for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.