Description

Isoquinoline, 1,2,3,4-Tetrahydro-1,3-Dimethyl-7-Nitro-, (1R,3R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector where specific stereochemistry is critical for biological activity. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where the specific (1R,3R) configuration can influence biological efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling new synthetic routes and the exploration of structure-activity relationships (SAR).

Basic Information

Product Name	Isoquinoline, 1,2,3,4-Tetrahydro-1,3-Dimethyl-7-Nitro-, (1R,3R)- (9Ci)
CAS No.	791048-46-9
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	(1R,3R)-1,3-Dimethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline; (1R,3R)-1,3-Dimethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline; 7-Nitro-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline (1R,3R)-isomer; (R,R)-1,3-Dimethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-1,3-dimethyl-7-nitroisoquinoline, (1R,3R)-; Tetrahydroisoquinoline derivative 791048-46-9; Chiral nitro-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our Isoquinoline, 1,2,3,4-Tetrahydro-1,3-Dimethyl-7-Nitro-, (1R,3R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We adhere to cGMP standards where applicable, and specifications can be aligned with customer-specific requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.