Description

Ethanone, 1-Spiro[(1R,2R,4S)-Bicyclo[2.2.1]Hept-2-Ene-7,1-Cyclopropan]-2-Yl- is a high-purity, chiral spirocyclic ketone building block of significant interest in advanced organic synthesis. Its unique and rigid three-dimensional structure makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex stereochemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides where its spirocyclic framework can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research of advanced organic materials, such as liquid crystals or polymers with specific stereogenic properties.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic chemistry, particularly in reactions involving strained ring systems and stereoselective transformations.

Basic Information

Product Name	Ethanone, 1-Spiro[(1R,2R,4S)-Bicyclo[2.2.1]Hept-2-Ene-7,1-Cyclopropan]-2-Yl-
CAS No.	790260-14-9
Molecular Formula	C12H14O
Molecular Weight	174.24 g/mol
Synonyms	1-[(1R,2R,4S)-Spiro[bicyclo[2.2.1]hept-2-ene-7,1'-cyclopropan]-2'-yl]ethanone; (1R,2R,4S)-2-Acetylspiro[bicyclo[2.2.1]hept-2-ene-7,1'-cyclopropane]; Spiro[bicyclo[2.2.1]hept-2-ene-7,1'-cyclopropane]-2'-yl ethanone, (1R,2R,4S)-; Chiral Norbornene-Spirocyclopropane Ketone; (1R,2R,4S)-2-Acetyl-7-spirocyclopropylnorbornene
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; containers should be kept tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.