Description

n-tert-Butoxycarbonyl 3-Iodotyramine is a protected derivative of the biogenic amine tyramine, featuring both a Boc-protected amine and an iodine substituent on the aromatic ring. This compound is a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its dual functional handles that enable selective chemical transformations. It is primarily utilized by research institutions and pharmaceutical R&D departments for the development of novel bioactive molecules, including potential drug candidates and radiopharmaceutical precursors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting neurological or hormonal pathways.
• Peptide Chemistry: Used to incorporate iodotyrosine analogs into synthetic peptides for structure-activity relationship (SAR) studies.
• Radiopharmaceutical Precursor: Serves as a starting material for the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Chemical Biology Probes: Enables the creation of tagged molecules for studying biological processes and protein interactions.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive aryl iodide moiety.
• Protecting Group Strategy: The Boc group allows for orthogonal deprotection in multi-step synthetic sequences.

Basic Information

Item	Detail
Product Name	n-tert-Butoxycarbonyl 3-Iodotyramine
CAS No.	788824-50-0
Molecular Formula	C13H18INO3
Molecular Weight	363.19 g/mol
Synonyms	Boc-3-Iodotyramine; tert-Butyl (4-(2-aminoethyl)-2-iodophenyl)carbamate; 3-Iodo-N-Boc-tyramine; 2-Iodo-4-[2-[(tert-butoxycarbonyl)amino]ethyl]phenol; N-Boc-3-iodotyramine; N-(tert-Butoxycarbonyl)-3-iodotyramine; 788824-50-0; Tyramine, 3-iodo-, N-Boc derivative
EINECS	Contact for details

Quality Control

Our n-tert-Butoxycarbonyl 3-Iodotyramine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.