Description

Spiro[Isoindoline-1,4'-Piperidin]-3-One Hcl is a high-purity organic building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its complex spirocyclic structure, which serves as a key scaffold in medicinal chemistry research and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel bioactive molecules, particularly within the central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the spiro[isoindoline-1,4'-piperidine] moiety into more complex molecular architectures.
• Academic & R&D Laboratories: Serves as a reference standard and starting material for novel synthetic methodologies and pharmacological investigations.

Basic Information

Product Name	Spiro[Isoindoline-1,4'-Piperidin]-3-One Hydrochloride
CAS No.	788812-21-5
Molecular Formula	C12H14N2O·HCl
Molecular Weight	238.71 g/mol
Synonyms	Spiro[isoindoline-1,4'-piperidin]-3-one hydrochloride; 3-Oxospiro[isoindoline-1,4'-piperidine] hydrochloride; 1',3'-Dihydrospiro[isoindole-1,4'-piperidin]-3-one HCl; 788812-21-5; Spiro(isoindoline-1,4'-piperidin)-3-one HCl salt
EINECS	Contact for details

Quality Control

Every batch of Spiro[Isoindoline-1,4'-Piperidin]-3-One Hcl is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for advanced research applications. A detailed Certificate of Analysis (COA) with specifications for assay, purity (by HPLC), and related substances is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.