Description

5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Ol is a high-purity, heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate. Its value lies in its unique fused bicyclic structure, which makes it a versatile building block for the synthesis of complex bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of complex naphthyridine and polyheterocyclic frameworks for various applications.
• Process Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Ol
CAS No.	785774-74-5
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	3-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine; 5,6,7,8-Tetrahydro-1,6-naphthyridin-3-ol; 1,6-Naphthyridin-3-ol, 5,6,7,8-tetrahydro-; THN-3-ol; 3-Hydroxytetrahydro-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.