Description

Cyclopenta[C]Pyrrole-1-Carboxylic Acid, 4,4-Difluorooctahydro- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused pyrrole-carboxylic acid structure with strategic fluorine substitution. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, complex molecules with enhanced metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in CNS-targeting therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated, conformationally constrained scaffold.
• Agrochemical Synthesis: Serves as a precursor for developing new generation pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology Probes: Utilized in the design and synthesis of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in organic synthesis and fluorine chemistry.

Basic Information

Product Name	Cyclopenta[C]Pyrrole-1-Carboxylic Acid, 4,4-Difluorooctahydro- (9Ci)
CAS No.	783325-80-4
Molecular Formula	C8H9F2NO2
Molecular Weight	189.16 g/mol
Synonyms	4,4-Difluorooctahydrocyclopenta[c]pyrrole-1-carboxylic acid; Octahydro-4,4-difluorocyclopenta[c]pyrrole-1-carboxylic acid; 4,4-Difluorooctahydro-1H-cyclopenta[c]pyrrole-1-carboxylic Acid; 1H-Cyclopenta[c]pyrrole-1-carboxylic acid, octahydro-4,4-difluoro-; 783325-80-4; 4,4-Difluorooctahydrocyclopentapyrrole-1-carboxylic acid; Difluorinated cyclopentapyrrole carboxylate
EINECS	Contact for details

Quality Control

Our Cyclopenta[C]Pyrrole-1-Carboxylic Acid, 4,4-Difluorooctahydro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.