Description

2,2-Difluoro-2-(quinolin-8-yl)ethanamine is a specialized fluorinated quinoline derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroethylamine moiety adjacent to the quinoline heterocycle, enabling precise molecular modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating novel chelating ligands in catalysis and material science.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions and constructing complex fluorinated molecular architectures.
• Chemical Biology Probes: Utilized in the design of fluorescent tags or molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2,2-Difluoro-2-(quinolin-8-yl)ethanamine
CAS No.	780769-67-7
Molecular Formula	C₁₁H₁₀F₂N₂
Molecular Weight	208.21 g/mol
Synonyms	8-Quinolineethanamine, 2,2-difluoro-; 2,2-Difluoro-2-(8-quinolyl)ethylamine; 2-(Quinolin-8-yl)-2,2-difluoroethanamine; 2,2-Difluoro-2-(8-quinolinyl)ethanamine; 780769-67-7; Ethanamine, 2,2-difluoro-2-(8-quinolinyl)-
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(quinolin-8-yl)ethanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.