Description

4-Piperidinecarboxamide,2-Methyl-,cis-(9Ci) is a high-purity, stereochemically defined piperidine derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise structural control for complex molecule development. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, process chemistry, and the synthesis of specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Utilized as a stereocontrolled building block in the synthesis of complex natural products and other bioactive molecules requiring specific cis-configuration.
• Agrochemical Research: Serves as a precursor in the development of new generation pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: A valuable reagent for synthetic chemistry studies in universities and research institutes focusing on heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Piperidinecarboxamide,2-Methyl-,cis-(9Ci)
CAS No.	780732-78-7
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	cis-2-Methylpiperidine-4-carboxamide; (3R,5S)-2-Methyl-3,5-piperidinedicarboxamide (related isomer); 2-Methyl-4-piperidinecarboxamide, cis-; 4-Carbamoyl-2-methylpiperidine, cis-; 2-Methylpiperidine-4-carboxylic acid amide, cis-; cis-2-Methyl-4-piperidinecarboxamide; 780732-78-7; 4-Piperidinecarboxamide, 2-methyl-, (3R,5S)-rel-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity research chemicals. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.