Description

2-[Bis(1,1-Dimethylethyl)Phosphino]-N,n-Diethyl-Benzamide is a specialized organophosphorus ligand with a sterically hindered, electron-rich phosphine center. This compound is highly valued for its role in facilitating challenging cross-coupling and hydrogenation reactions in fine chemical and pharmaceutical synthesis. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance catalysts for complex molecular transformations.

Application

• Pharmaceutical Intermediate Synthesis: As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig amination) for constructing complex drug molecules.
• Agrochemical Manufacturing: Used in catalytic processes to create novel, high-performance active ingredients for crop protection products.
• Catalyst Development: Serves as a critical component in the design and preparation of homogeneous transition metal catalysts for asymmetric hydrogenation and other stereoselective reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and polymers where precise metal-mediated coupling is essential.
• Academic & Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research laboratories.

Basic Information

Product Name	2-[Bis(1,1-Dimethylethyl)Phosphino]-N,n-Diethyl-Benzamide
CAS No.	779339-46-7
Molecular Formula	C19H32NOP
Molecular Weight	321.44 g/mol
Synonyms	2-(Di-tert-butylphosphino)-N,N-diethylbenzamide; Di-tert-butyl(2-(diethylcarbamoyl)phenyl)phosphine; N,N-Diethyl-2-(di-tert-butylphosphino)benzamide; 2-(Di-tert-butylphosphino)-N,N-diethyl-benzamide; Benzamide, 2-[bis(1,1-dimethylethyl)phosphino]-N,N-diethyl-; DTBP-DEBA; Ligand 779339-46-7
EINECS	Contact for details

Quality Control

Our production of 2-[Bis(1,1-Dimethylethyl)Phosphino]-N,n-Diethyl-Benzamide adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing lot-specific results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain optimal performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.