Description

tert-Butyl 4-oxo-1-azaspiro[5.5]undecane-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular architectures in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting specific biological pathways.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and receptor interactions in biological systems.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Custom Synthesis Building Block: Supplied to fine chemical companies for the preparation of more complex, customer-specific intermediates.

Basic Information

Product Name	tert-Butyl 4-oxo-1-azaspiro[5.5]undecane-1-carboxylate
CAS No.	778647-35-1
Molecular Formula	C15H25NO3
Molecular Weight	267.36 g/mol
Synonyms	1-Azaspiro[5.5]undecane-1-carboxylic acid, 4-oxo-, 1,1-dimethylethyl ester; 1-tert-Butoxycarbonyl-4-oxo-1-azaspiro[5.5]undecane; 4-Oxo-1-azaspiro[5.5]undecane-1-carboxylic acid tert-butyl ester; Boc-4-oxo-1-azaspiro[5.5]undecane; tert-Butyl 4-oxo-1-azaspiro[5.5]undecane-1-carboxylate; 1-Boc-4-oxo-1-azaspiro[5.5]undecane; N-Boc-4-oxo-1-azaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-oxo-1-azaspiro[5.5]undecane-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.