Description

(R)-3-Amino-3-(2,4-Dichloro-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a dichlorophenyl moiety. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutic agents and crop protection products. The specific stereochemistry and functional groups make it a valuable precursor for targeted synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex, optically active Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides where the specific stereochemistry influences biological activity.
• Peptidomimetics: Incorporated into the design and synthesis of peptide analogs and mimetics for biochemical research and drug discovery.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a starting material for creating labeled compounds or probes used in mechanistic studies and target identification.

Basic Information

Product Name	(R)-3-Amino-3-(2,4-Dichloro-Phenyl)-Propionic Acid
CAS No.	778571-53-2
Molecular Formula	C9H9Cl2NO2
Molecular Weight	234.08 g/mol
Synonyms	(R)-3-Amino-3-(2,4-dichlorophenyl)propanoic acid; (R)-2,4-Dichloro-β-phenyl-β-alanine; (R)-3-Amino-3-(2,4-dichlorophenyl)propionic acid; (R)-β-Amino-2,4-dichlorohydrocinnamic acid; (R)-3-(2,4-Dichlorophenyl)-3-aminopropanoic acid; D-3-Amino-3-(2,4-dichlorophenyl)propionic acid; (R)-3-(2,4-Dichlorophenyl)-β-alanine
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(2,4-Dichloro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.