Description

Butanamide, 2-Amino-3-Hydroxy-N,n-Dimethyl-, [R-(R*,S*)]- (9Ci) is a chiral, multifunctional amide derivative of significant interest in advanced organic synthesis. Its core value proposition lies in its unique stereochemistry and functional group array, making it a versatile building block for creating complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality is crucial for bioactivity.
• Chemical Research: Serves as a valuable reference standard and building block in academic and industrial laboratories for methodological development in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity, optically active intermediates.
• Bioconjugate Chemistry: Potential use in linker molecules for antibody-drug conjugates (ADCs) and other targeted therapeutic platforms due to its functional handles.

Basic Information

Product Name	Butanamide, 2-Amino-3-Hydroxy-N,n-Dimethyl-, [R-(R*,S*)]- (9Ci)
CAS No.	777021-86-0
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	2-Amino-3-hydroxy-N,N-dimethylbutanamide; (2R,3S)-2-Amino-3-hydroxy-N,N-dimethylbutyramide; (2R,3S)-2-Amino-3-hydroxy-N,N-dimethylbutanamide; (2R,3S)-AHDB; N,N-Dimethyl-2-amino-3-hydroxybutyramide; (R*,S*)-2-Amino-3-hydroxy-N,N-dimethylbutanamide; (2R,3S)-2-Amino-3-hydroxybutyric acid dimethylamide
EINECS	Contact for details

Quality Control

Our Butanamide, 2-Amino-3-Hydroxy-N,n-Dimethyl-, [R-(R*,S*)]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.