Description

2-Naphthalenamine,6-Fluoro-1,2,3,4-Tetrahydro-7-Methoxy-,(2R)-(9Ci) is a chiral, fluorinated tetrahydro-naphthalenamine derivative, a sophisticated organic intermediate of significant interest in advanced synthesis. Its value lies in its unique molecular architecture, which combines a stereogenic center with fluorine and methoxy substituents, enabling precise modifications in complex molecular frameworks. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom and specific stereochemistry can enhance biological activity and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex polycyclic structures in academic and industrial organic chemistry laboratories.
• Material Science Research: Potential intermediate in the synthesis of specialty polymers or organic electronic materials that require specific fluorinated aromatic amines.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Naphthalenamine,6-Fluoro-1,2,3,4-Tetrahydro-7-Methoxy-,(2R)-(9Ci)
CAS No.	775564-35-7
Molecular Formula	C11H14FNO
Molecular Weight	195.23 g/mol
Synonyms	(2R)-6-Fluoro-7-methoxy-1,2,3,4-tetrahydro-2-naphthalenamine; (R)-6-Fluoro-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine; 6-Fluoro-7-methoxy-1,2,3,4-tetrahydro-2-naphthalenamine (R)-; (2R)-6-Fluoro-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine; 775564-35-7; (R)-6-Fluoro-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine; (2R)-6-Fluoro-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this advanced intermediate, quality is assured through comprehensive analytical techniques including HPLC, GC, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.