Description

(1-Aza-Bicyclo[2.2.2]Oct-3-Yl)-(4-Methoxy-Benzyl)-Amine is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic amine structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Ligand and Probe Synthesis: Used in the creation of specific ligands for biological target validation and biochemical assay development.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic & Institutional R&D: Utilized in university and government research projects focused on organic synthesis methodology and novel heterocyclic compounds.

Basic Information

Product Name	(1-Aza-Bicyclo[2.2.2]Oct-3-Yl)-(4-Methoxy-Benzyl)-Amine
CAS No.	774554-52-8
Molecular Formula	C15H22N2O
Molecular Weight	246.35 g/mol
Synonyms	3-[(4-Methoxybenzyl)amino]quinuclidine; 1-Azabicyclo[2.2.2]octan-3-amine, N-[(4-methoxyphenyl)methyl]-; N-(4-Methoxybenzyl)quinuclidin-3-amine; Quinuclidin-3-yl-(4-methoxy-benzyl)-amine; (4-Methoxy-benzyl)-(1-aza-bicyclo[2.2.2]oct-3-yl)-amine
EINECS	Contact for details

Quality Control

Our (1-Aza-Bicyclo[2.2.2]Oct-3-Yl)-(4-Methoxy-Benzyl)-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.