Description

[[(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)Sulfonyl](Methyl)Amino]Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic sulfonamide structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinazolinone-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Biochemical Tool Compound: Serves as a precursor for developing enzyme inhibitors or receptor modulators in biochemical assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific sulfonamide and acetic acid functionalities.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the production of custom, high-value specialty chemicals.

Basic Information

Product Name	[[(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)Sulfonyl](Methyl)Amino]Acetic Acid
CAS No.	773877-46-6
Molecular Formula	C₁₃H₁₅N₃O₆S
Molecular Weight	341.34 g/mol
Synonyms	N-[[(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-6-quinazolinyl)sulfonyl]-N-methylglycine; 2-[[(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-6-yl)sulfonyl](methyl)amino]acetic acid; (1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonyl)(methyl)aminoacetic acid; Glycine, N-[[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-6-quinazolinyl)sulfonyl]-N-methyl-; CAS 773877-46-6
EINECS	Contact for details

Quality Control

Our [[(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)Sulfonyl](Methyl)Amino]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.