Description

2'-Hydroxymethyl-Biphenyl-3-Carboxylic Acid is a versatile biphenyl derivative that serves as a key chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a benzylic alcohol functional group, makes it highly valuable for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, especially for anti-inflammatory and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its biphenyl core for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a foundational structure for creating chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways due to its multifunctional reactivity.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value organic compounds for various industrial applications.

Basic Information

Product Name	2'-Hydroxymethyl-Biphenyl-3-Carboxylic Acid
CAS No.	773872-29-0
Molecular Formula	C14H12O3
Molecular Weight	228.24 g/mol
Synonyms	[2-(Hydroxymethyl)phenyl]-3-benzoic Acid; 3-Biphenylcarboxylic Acid, 2'-(hydroxymethyl)-; 2'-(Hydroxymethyl)biphenyl-3-carboxylic Acid; 2-(Hydroxymethyl)-[1,1'-biphenyl]-3-carboxylic Acid; Biphenyl-3-carboxylic acid, 2'-(hydroxymethyl)-; (1,1'-Biphenyl)-3-carboxylic acid, 2'-(hydroxymethyl)-; 2'-Hydroxymethyl-3-biphenylcarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2'-Hydroxymethyl-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.