Description

2-Chloro-5,8-Difluoroquinoline is a high-value, multi-functional halogenated quinoline derivative serving as a critical synthetic intermediate. Its molecular structure, featuring strategically placed chlorine and fluorine atoms, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoroquinoline scaffold contributes to efficacy and environmental profile.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in organic chemistry research as a versatile substrate for cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex functionalities.
• Fluorescent Probe Development: Utilized in the design and synthesis of specialized fluorescent dyes and probes for biochemical sensing and imaging applications.

Basic Information

Product Name	2-Chloro-5,8-Difluoroquinoline
CAS No.	773148-82-6
Molecular Formula	C9H4ClF2N
Molecular Weight	199.59 g/mol
Synonyms	5,8-Difluoro-2-chloroquinoline; 2-Chloro-5,8-difluoroquinoline; Quinoline, 2-chloro-5,8-difluoro-; 773148-82-6; 2-Chloro-5,8-difluoro-quinoline; 5,8-Difluoro-2-chloro-quinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5,8-Difluoroquinoline is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.