Description

2-Methoxy-5-(Trifluoromethyl)Cinnamic Acid is a high-value, multi-functional cinnamic acid derivative distinguished by its methoxy and trifluoromethyl substituents. This compound is a critical pharmaceutical intermediate and advanced building block for the synthesis of complex molecules, offering unique electronic and steric properties. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty electronic materials, where its rigid, conjugated structure contributes to desired optical and electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex biaryl systems for various fine chemical applications.
• Chemical Research & Development: A versatile scaffold for academic and industrial research into new fluorinated compounds and their physicochemical behaviors.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Cinnamic Acid
CAS No.	773133-16-7
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	(E)-3-[2-Methoxy-5-(trifluoromethyl)phenyl]acrylic acid; 3-(2-Methoxy-5-(trifluoromethyl)phenyl)-2-propenoic acid; 2-Methoxy-α,5-bis(trifluoromethyl)cinnamic acid (common misnomer); 2-Methoxy-5-trifluoromethylcinnamic acid; (E)-2-Methoxy-5-(trifluoromethyl)cinnamic acid; trans-2-Methoxy-5-(trifluoromethyl)cinnamic acid; 5-(Trifluoromethyl)-2-methoxycinnamic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-5-(Trifluoromethyl)Cinnamic Acid is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.