Description

4-Chloro-2-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, enables precise modulation of electronic and steric properties in target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its fluorinated aromatic core.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to impart specific properties like hydrophobicity or chemical resistance to polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for studying structure-activity relationships and developing novel synthetic methodologies.
• Fluorine Chemistry: Valuable synthon for introducing the trifluoromethyl group into complex molecular architectures.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)Cinnamic Acid
CAS No.	773132-29-9
Molecular Formula	C10H6ClF3O2
Molecular Weight	250.60 g/mol
Synonyms	(E)-3-[4-Chloro-2-(trifluoromethyl)phenyl]acrylic acid; 4-Chloro-α-(trifluoromethyl)cinnamic acid; 2-Trifluoromethyl-4-chlorocinnamic acid; (2E)-3-[4-Chloro-2-(trifluoromethyl)phenyl]prop-2-enoic acid; 4-Chloro-2-trifluoromethylcinnamic acid; 3-(4-Chloro-2-(trifluoromethyl)phenyl)acrylic acid; 4-Chloro-2-(trifluoromethyl)benzeneacrylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethyl)Cinnamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.