Description

2-Propenoic Acid, 3-(3-Chloro-5-Fluorophenyl)- is a specialized fluorinated and chlorinated acrylic acid derivative, serving as a high-value synthetic intermediate. Its unique structure makes it a critical building block for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity of the fluorophenyl moiety.
• Specialty Polymer Monomer: Serves as a functional monomer for creating polymers with specific properties like chemical resistance, adhesion, or tailored surface characteristics.
• Liquid Crystal & OLED Materials: A potential building block for advanced electronic materials used in displays and organic light-emitting diodes.
• Chemical Research & Development: Essential for academic and industrial R&D focused on fluorinated organic compounds and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Propenoic Acid, 3-(3-Chloro-5-Fluorophenyl)-
CAS No.	773132-05-1
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	3-(3-Chloro-5-fluorophenyl)acrylic acid; (E)-3-(3-Chloro-5-fluorophenyl)acrylic acid; 3-(3-Chloro-5-fluorophenyl)-2-propenoic acid; 3-(3-Chloro-5-fluorophenyl)prop-2-enoic acid; 3-CFA (abbreviation); 3-Chloro-5-fluorocinnamic acid; trans-3-(3-Chloro-5-fluorophenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 2-Propenoic Acid, 3-(3-Chloro-5-Fluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.