Description

4-(5-(Trifluoromethyl)-2-Pyridyloxy)Benzoic Acid is a high-value, fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylpyridyloxy moiety, makes it an essential intermediate for developing novel active ingredients with enhanced properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl group can improve bioavailability and environmental stability.
• Material Science Research: Employed as a monomer or functional additive in the development of specialty polymers and liquid crystal materials.
• Organic Light-Emitting Diodes (OLEDs): Investigated as an electron-transport or host material component in the fabrication of advanced OLED devices.
• Chemical Biology Probes: Serves as a scaffold for creating fluorinated probes and tags used in bioimaging and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic intermediates.

Basic Information

Product Name	4-(5-(Trifluoromethyl)-2-Pyridyloxy)Benzoic Acid
CAS No.	773108-67-1
Molecular Formula	C13H8F3NO3
Molecular Weight	283.20 g/mol
Synonyms	4-[(5-(Trifluoromethyl)pyridin-2-yl)oxy]benzoic acid; Benzoic acid, 4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-; 4-(5-Trifluoromethyl-2-pyridyloxy)benzoic acid; 2-Pyridyloxybenzoic acid derivative; [5-(Trifluoromethyl)pyridin-2-yl]oxybenzoic acid; Fluorinated pyridyloxy benzoic acid; TFPBA (abbrev.); CAS 773108-67-1
EINECS	Contact for details

Quality Control

Our 4-(5-(Trifluoromethyl)-2-Pyridyloxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.