Description

6-Bromo-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters because it serves as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its fused quinoline core.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes to study biological processes.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	6-Bromo-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	773033-36-6
Molecular Formula	C11H12BrNO2
Molecular Weight	270.12 g/mol
Synonyms	Methyl 6-bromo-1,2,3,4-tetrahydroquinoline-2-carboxylate; 6-Bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 6-bromo-1,2,3,4-tetrahydro-, methyl ester; 6-Bromo-1,2,3,4-tetrahydroquinoline-2-carboxylic acid methyl ester; Methyl 6-bromo-3,4-dihydro-2H-quinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.