Description

2-Methyl-5-(Trifluoromethyl)Benzylamine is a versatile trifluoromethyl-substituted benzylamine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the benzylamine moiety and the electron-withdrawing trifluoromethyl group, which can significantly alter the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty chemicals and materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, or advanced organic frameworks (MOFs/COFs) with tailored properties.
• Chemical Biology Probe Development: Useful for creating molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Benzylamine
CAS No.	771572-44-2
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	α-Methyl-3-(trifluoromethyl)benzylamine; (2-Methyl-5-(trifluoromethyl)phenyl)methanamine; 1-[2-Methyl-5-(trifluoromethyl)phenyl]methanamine; 2-Methyl-α-(trifluoromethyl)benzylamine; 5-(Trifluoromethyl)-2-methylbenzylamine; 2-Methyl-5-trifluoromethylbenzylamine; Benzenemethanamine, 2-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Benzylamine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (nitrogen or argon). Keep away from strong oxidizing agents, acids, and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.