Description

Spiro[Bicyclo[3.2.0]Heptane-6,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci) is a high-purity, synthetically valuable spirocyclic compound with the CAS number 770728-75-1. This specialized intermediate is crucial for advanced organic synthesis, particularly in constructing complex, three-dimensional molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring rigid, spirocyclic scaffolds to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its unique structure can contribute to enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and specialty materials with tailored thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for methodological studies, including cycloaddition reactions and the construction of strained ring systems.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex odorants and flavor compounds that benefit from its bicyclic framework.

Basic Information

Product Name	Spiro[Bicyclo[3.2.0]Heptane-6,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci)
CAS No.	770728-75-1
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	Ethyl Spiro[bicyclo[3.2.0]heptane-6,1'-cyclopropane]-2-carboxylate; Ethyl 1'-Oxaspiro[cyclopropane-1,6'-bicyclo[3.2.0]heptane]-2'-carboxylate; Spiro[bicyclo[3.2.0]heptane-6,1'-cyclopropane]-2-carboxylic acid ethyl ester; 770728-75-1; Ethyl 2-oxaspiro[3.5]nonane-1-carboxylate (related structural isomer); Bicyclo[3.2.0]heptane-6-spiro-1'-cyclopropane-2-carboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[3.2.0]Heptane-6,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.