Description

Spiro[Bicyclo[2.2.1]Heptane-2,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci) is a high-purity, specialized organic building block featuring a unique spirocyclic and bicyclic fused ring system. This complex molecular architecture makes it a valuable intermediate for advanced research and development in pharmaceutical chemistry and materials science. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. The compound, with CAS No. 770728-70-6, is supplied to meet the stringent requirements of modern synthetic organic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated scaffold or precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides where its rigid, three-dimensional structure can impart unique biological activity.
• Material Science: Acts as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties due to its strained ring systems.
• Asymmetric Synthesis: Employed as a chiral building block or auxiliary in stereoselective synthesis to construct complex molecules with defined three-dimensional shapes.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for transition metal catalysis, leveraging its unique steric and electronic properties.
• Academic & Institutional Research: A key reagent for methodological studies in organic synthesis, exploring new cycloaddition or ring-opening reactions.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci)
CAS No.	770728-70-6
Molecular Formula	C12H16O2
Molecular Weight	192.25 g/mol
Synonyms	Ethyl Spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropane]-2-carboxylate; Ethyl 1'-Azaspiro[bicyclo[2.2.1]heptane-2,2'-cyclopropane]-1-carboxylate (related structural isomer); Bicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-cyclopropanediyl-, ethyl ester; 770728-70-6; Spiro[norbornane-2,1'-cyclopropane]-2-carboxylic acid ethyl ester; Ethyl 2-spiro(bicyclo[2.2.1]heptane-2,1'-cyclopropane)carboxylate.
EINECS	Contact for details

Quality Control

Every batch of Spiro[Bicyclo[2.2.1]Heptane-2,1-Cyclopropane]-2-Carboxylic Acid, Ethyl Ester (9Ci) is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including results from HPLC, GC, NMR, and mass spectrometry is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under an inert atmosphere (nitrogen or argon), please contact us.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Standard Grade)
Purity (HPLC/GC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.