Description

Ethyl 3-(3-Chloro-5-Cyanophenoxy)-2-Fluoro-4-Nitrobenzeneacetate is a high-value, multi-functional aromatic ester intermediate designed for advanced chemical synthesis. Its complex structure, featuring chloro, cyano, fluoro, and nitro substituents, makes it a critical building block for creating molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Synthesis: Serves as a core building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system for bioactivity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced organic electronic materials due to its polarizable aromatic core and electron-withdrawing groups, which influence charge transport and luminescent properties.
• Dye & Pigment Intermediate: Functions as a sophisticated intermediate for synthesizing specialized dyes and high-performance pigments, where the nitro and cyano groups contribute to color strength and stability.
• Polymer Modification: Employed to introduce functional side chains into polymer backbones, enhancing properties like thermal stability, solubility, or specific molecular recognition.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of reactive halogen atoms, enabling complex molecular architecture construction.

Basic Information

Product Name	Ethyl 3-(3-Chloro-5-Cyanophenoxy)-2-Fluoro-4-Nitrobenzeneacetate
CAS No.	770719-10-3
Molecular Formula	C₁₇H₁₂ClFN₂O₅
Molecular Weight	378.74 g/mol
Synonyms	Ethyl 2-fluoro-4-nitro-3-[(3-chloro-5-cyanophenoxy)]benzeneacetate; 2-Fluoro-4-nitro-3-(3-chloro-5-cyanophenoxy)benzeneacetic acid ethyl ester; Benzeneacetic acid, 2-fluoro-4-nitro-3-[(3-chloro-5-cyanophenoxy)]-, ethyl ester; Ethyl [2-fluoro-4-nitro-3-(3-chloro-5-cyanophenoxy)]phenylacetate; 770719-10-3; Ethyl 3-(3-chloro-5-cyanophenoxy)-2-fluoro-4-nitrobenzeneacetate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Chloro-5-Cyanophenoxy)-2-Fluoro-4-Nitrobenzeneacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.