Description

6-Bromoquinazoline-4-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant importance in modern organic synthesis. Its core value lies in its functionalized quinazoline scaffold, which serves as a critical precursor for constructing more complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis for client projects.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic chemistry and new reaction development.

Basic Information

Product Name	6-Bromoquinazoline-4-Carboxylic Acid
CAS No.	769916-07-6
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.06 g/mol
Synonyms	6-Bromo-4-quinazolinecarboxylic acid; 4-Quinazolinecarboxylic acid, 6-bromo-; 6-Bromoquinazoline-4-carboxylic acid; Quinazoline-4-carboxylic acid, 6-bromo-; 769916-07-6; 6-Bromo-quinazoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromoquinazoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.