Description

Phosphonic Acid, (1-Diazo-2-Oxopropyl)-, Monomethyl Ester is a specialized organophosphorus compound featuring a reactive diazo and ketone functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized polymers and surface-modifying agents.
• Chemical Biology Probes: Utilized in the creation of activity-based probes for studying biological pathways.
• Cross-Coupling Reactions: Acts as a reagent in metal-catalyzed cross-coupling reactions to form carbon-phosphorus bonds.
• Ligand Synthesis: Intermediate for the preparation of specialized phosphonate-based ligands for catalysis.

Basic Information

Product Name	Phosphonic Acid, (1-Diazo-2-Oxopropyl)-, Monomethyl Ester
CAS No.	766475-74-5
Molecular Formula	C5H9N2O4P
Molecular Weight	192.11 g/mol
Synonyms	Monomethyl (1-Diazo-2-oxopropyl)phosphonate; (1-Diazo-2-oxopropyl)phosphonic Acid Monomethyl Ester; Diazoacetonylphosphonic Acid Monomethyl Ester; Methyl (1-Diazo-2-oxopropyl)phosphonate; 1-Diazo-2-oxopropylphosphonic Acid Methyl Ester; Methyl 1-Diazo-2-oxopropylphosphonate; Phosphonic acid, P-(1-diazo-2-oxopropyl)-, monomethyl ester
EINECS	Contact for details

Quality Control

Our production of Phosphonic Acid, (1-Diazo-2-Oxopropyl)-, Monomethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.