Description

4-(4-Chlorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines halogenated phenyl and fluorinated benzoic acid moieties, enabling precise structural modifications for developing novel compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated characteristics.
• Chemical Biology Probe Synthesis: Utilized as a core structure for developing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	4-(4-Chlorophenyl)-2-Fluorobenzoic Acid
CAS No.	764722-93-2
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	2-Fluoro-4'-(chloro)[1,1'-biphenyl]-4-carboxylic Acid; 4'-Chloro-2-fluoro[1,1'-biphenyl]-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-chloro-2-fluoro-; 4-(4-Chlorophenyl)-2-fluorobenzoic acid; 2-Fluoro-4-(4-chlorophenyl)benzoic Acid; 4'-Chloro-2-fluorobiphenyl-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chlorophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.