Description

n-(2,2-Difluoroethyl)-4-(6-Fluoro-3-Oxo-1H-Pyrazolo[4,3-C]Cinnolin-2(3H)-Yl)Benzamide is a high-purity, complex heterocyclic compound designed for advanced research and development. This specialized chemical serves as a critical pharmaceutical intermediate or active pharmaceutical ingredient (API) building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, neurology, and other targeted disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) therapeutic areas.
• API (Active Pharmaceutical Ingredient) Development: Serves as a core structural moiety for developing new chemical entities with potential biological activity.
• Biochemical Research: Used in high-throughput screening and as a tool compound for studying enzyme inhibition or receptor binding assays.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	n-(2,2-Difluoroethyl)-4-(6-Fluoro-3-Oxo-1H-Pyrazolo[4,3-C]Cinnolin-2(3H)-Yl)Benzamide
CAS No.	763142-16-1
Molecular Formula	C20H14F3N5O2
Molecular Weight	413.36 g/mol
Synonyms	4-(6-Fluoro-3-oxo-1H-pyrazolo[4,3-c]cinnolin-2(3H)-yl)-N-(2,2-difluoroethyl)benzamide; 763142-16-1; Benzamide, N-(2,2-difluoroethyl)-4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]cinnolin-2(3H)-yl)-; N-(2,2-Difluoroethyl)-4-(6-fluoro-3-oxo-1H,2H,3H-pyrazolo[4,3-c]cinnolin-2-yl)benzamide; 4-(6-Fluoro-3-oxo-1H-pyrazolo[4,3-c]cinnolin-2-yl)-N-(2,2-difluoroethyl)benzamide
EINECS	Contact for details

Quality Control

Our n-(2,2-Difluoroethyl)-4-(6-Fluoro-3-Oxo-1H-Pyrazolo[4,3-C]Cinnolin-2(3H)-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical specifications such as assay and impurity profiles. We support development with GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.