Description

1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4R)-Rel-(9Ci) CAS NO 761427-52-5 is a high-purity, stereochemically defined chiral diamine building block. This compound is critical for the synthesis of sophisticated ligands and catalysts used in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in their synthetic pathways.

Application

• Asymmetric Catalysis: As a key precursor for chiral ligands and organocatalysts in enantioselective hydrogenation, epoxidation, and C-C bond-forming reactions.
• Pharmaceutical Intermediates: In the synthesis of active pharmaceutical ingredients (APIs) where its rigid, chiral backbone is incorporated to impart specific biological activity.
• Chiral Resolving Agents: Used to separate enantiomers of racemic mixtures in analytical and preparative-scale chemistry.
• Coordination Chemistry: For constructing metal-organic frameworks (MOFs) and complexes with applications in catalysis and material science.
• Agrochemical Synthesis: As a building block for chiral herbicides, fungicides, and plant growth regulators.
• Polymer Modification: To introduce chiral centers into polymers, potentially altering their physical and optical properties.

Basic Information

Product Name	1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4R)-Rel-(9Ci)
CAS No.	761427-52-5
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(1R,2R,4R)-4-Methylcyclohexane-1,2-diamine; (1R,2R,4R)-4-Methyl-1,2-cyclohexanediamine; (1R,2R,4R)-4-Methyl-1,2-diaminocyclohexane; rel-(1R,2R,4R)-4-Methylcyclohexane-1,2-diamine; (1R,2R,4R)-(-)-4-Methyl-1,2-diaminocyclohexane; Chiral 4-Methyl-1,2-cyclohexanediamine; (1R,2R,4R)-MCHDA
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4R)-Rel-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.