Description

1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral diamine building block. This compound matters as a critical ligand and precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral auxiliaries for catalysis and complex molecule construction. CAS No. 761426-11-3.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand for transition metal catalysts in enantioselective hydrogenation, hydroformylation, and C-C bond-forming reactions.
• Pharmaceutical Intermediates: A vital building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry for efficacy and safety.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and pesticides where stereochemistry impacts biological activity.
• Chiral Resolution Agents: Employed to separate enantiomers of racemic mixtures in analytical and preparative-scale applications.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored mechanical and optical properties.
• Coordination Chemistry: Forms stable complexes with various metals for applications in material science and catalysis.

Basic Information

Product Name	1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4S)-Rel-(9Ci)
CAS No.	761426-11-3
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(1R,2R,4S)-4-Methylcyclohexane-1,2-diamine; (1R,2R,4S)-4-Methyl-1,2-cyclohexanediamine; (1R,2R,4S)-4-Methylcyclohexane-trans-1,2-diamine; (1R,2R,4S)-4-Methyl-trans-1,2-diaminocyclohexane; trans-(1R,2R)-4-Methyl-1,2-cyclohexanediamine; (1R,2R,4S)-rel-4-Methylcyclohexane-1,2-diamine; Chiral 4-Methylcyclohexanediamine; MCHDA
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanediamine,4-Methyl-,(1R,2R,4S)-Rel-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and optical rotation measurement, to ensure compliance with exacting research and process chemistry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.