Description

Ethyl 2-(4-Bromophenyl)-2-Diazoacetate is a specialized diazo compound featuring a bromophenyl substituent, serving as a versatile building block in advanced organic synthesis. This compound is valued for its ability to act as a carbene precursor, enabling the construction of complex molecular frameworks through cyclopropanation and other metal-catalyzed transformations. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing complex heterocycles and strained ring systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactivity to create unique bioactive structures.
• Catalytic Cyclopropanation: Serves as a critical reagent in metal-catalyzed (e.g., Rh, Cu) cyclopropanation reactions to form three-membered carbocycles, a valuable motif in medicinal chemistry.
• Polymer & Material Science: Employed in the development of specialty polymers and functional materials where the diazo group facilitates cross-linking or introduces specific photoactive properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, enabling new C-H functionalization and C-C bond-forming reactions.

Basic Information

Product Name	Ethyl 2-(4-Bromophenyl)-2-Diazoacetate
CAS No.	758692-47-6
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	Ethyl (4-Bromophenyl)diazoacetate; 2-Diazo-2-(4-bromophenyl)acetic Acid Ethyl Ester; Ethyl α-Diazo-4-bromophenylacetate; Diazo(4-bromophenyl)acetic Acid Ethyl Ester; 4-Bromophenyldiazoacetic Acid Ethyl Ester; Ethyl 2-Diazo-2-(p-bromophenyl)acetate; p-Bromophenyldiazoacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Bromophenyl)-2-Diazoacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.