Description

n-(4-Bromobenzyl)-4-Fluorobenzylamine is a high-purity (97%) bifunctional aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromo and fluoro substituents on separate benzyl rings, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the halogenated benzyl groups can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to its halogen handles and amine functionality.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of advanced polymers, dendrimers, or organic frameworks with specific optical or electronic properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or affinity probes for studying biological pathways and target engagement.

Basic Information

Product Name	n-(4-Bromobenzyl)-4-Fluorobenzylamine
CAS No.	758682-96-1
Molecular Formula	C14H13BrFN
Molecular Weight	294.16 g/mol
Synonyms	1-[(4-Bromophenyl)methyl]-1-(4-fluorophenyl)methanamine; 4-Bromobenzyl(4-fluorobenzyl)amine; N-[(4-Bromophenyl)methyl]-1-(4-fluorophenyl)methanamine; N-(4-Bromobenzyl)-4-fluorobenzylamine; 1-(4-Bromobenzylamino)methyl-4-fluorobenzene; (4-Bromobenzyl)(4-fluorobenzyl)amine; 4-Fluoro-N-(4-bromobenzyl)benzylamine; α-[(4-Bromobenzyl)amino]-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our n-(4-Bromobenzyl)-4-Fluorobenzylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment, supporting your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.