Description

1-Oxa-8-Azaspiro[4.5]Decan-3-Ol (9Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique spirocyclic structure, which serves as a critical scaffold for developing novel pharmaceuticals and agrochemicals with targeted biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used as a core structural motif in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research and development of advanced polymers and functional materials with specific chemical properties.
• Chemical Biology Probe: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	1-Oxa-8-Azaspiro[4.5]Decan-3-Ol (9Ci)
CAS No.	757239-76-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	1-Oxa-8-azaspiro[4.5]decan-3-ol; 8-Aza-1-oxaspiro[4.5]decan-3-ol; 3-Hydroxy-1-oxa-8-azaspiro[4.5]decane; 1-Oxa-8-azaspiro[4.5]decan-3-ol (9CI); Spiro[1-oxa-8-azacyclopentane-2,1'-cyclopentane]-3-ol
EINECS	Contact for details

Quality Control

Our 1-Oxa-8-Azaspiro[4.5]Decan-3-Ol (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.