Description

1-(3-Fluorophenyl)-3-Methyl-1H-Pyrazole-5-Carboxylic Acid is a high-purity fluorinated pyrazole carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated aromatic ring and a carboxylic acid functional group, enabling precise modifications to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine-tuning the physicochemical properties of lead compounds. CAS No. 756752-22-4.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	1-(3-Fluorophenyl)-3-Methyl-1H-Pyrazole-5-Carboxylic Acid
CAS No.	756752-22-4
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	3-Methyl-1-(3-fluorophenyl)-1H-pyrazole-5-carboxylic acid; 1H-Pyrazole-5-carboxylic acid, 1-(3-fluorophenyl)-3-methyl-; 5-Carboxy-3-methyl-1-(3-fluorophenyl)pyrazole; 1-(3-Fluorophenyl)-3-methylpyrazole-5-carboxylic acid; 3-Methyl-1-(m-fluorophenyl)-1H-pyrazole-5-carboxylic acid; 756752-22-4; FC-0564; ZINC000257830509
EINECS	Contact for details

Quality Control

Our production of 1-(3-Fluorophenyl)-3-Methyl-1H-Pyrazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.