Description

1-(2,6-Dichloro-3-Fluorophenyl)Ethanol is a high-purity fluorinated aromatic alcohol building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the biological activity of the dichloro-fluorophenyl moiety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty monomers for high-performance polymers and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1-(2,6-Dichloro-3-Fluorophenyl)Ethanol
CAS No.	756520-66-8
Molecular Formula	C8H7Cl2FO
Molecular Weight	209.04 g/mol
Synonyms	(2,6-Dichloro-3-fluorophenyl)ethanol; 1-(2,6-Dichloro-3-fluorophenyl)ethan-1-ol; α-Methyl-2,6-dichloro-3-fluorobenzyl alcohol; 2,6-Dichloro-3-fluoro-α-methylbenzyl alcohol; 1-(2,6-Dichloro-3-fluorophenyl)ethyl alcohol; 756520-66-8; 2,6-Dichloro-3-fluoro-α-methylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(2,6-Dichloro-3-Fluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality, traceability, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.