Description

Aziridine, 2-Methyl-1-(1-Methylethyl)-3-Phenyl-, (2S,3S)- (9Ci) is a chiral, substituted aziridine derivative, a class of compounds known for their highly strained three-membered ring structure. This specific stereoisomer is valued as a versatile chiral building block and intermediate in advanced organic synthesis. It is particularly relevant for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require high-purity, stereochemically defined intermediates for the development of active ingredients and functional materials.

Application

This chiral aziridine serves as a key intermediate in sophisticated chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Used in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or as enzyme inhibitors.
• Agrochemical Synthesis: Acts as a precursor for chiral herbicides, fungicides, and insecticides, where stereochemistry can significantly influence biological activity.
• Ligand and Catalyst Development: Employed in the construction of chiral ligands for asymmetric catalysis and organocatalysts.
• Advanced Material Research: Utilized in polymer science for creating functionalized polymers with specific stereochemical properties.
• Academic and R&D Laboratories: Serves as a valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	Aziridine, 2-Methyl-1-(1-Methylethyl)-3-Phenyl-, (2S,3S)- (9Ci)
CAS No.	756411-91-3
Molecular Formula	C13H17N
Molecular Weight	187.28 g/mol
Synonyms	(2S,3S)-2-Methyl-1-isopropyl-3-phenylaziridine; (2S,3S)-1-Isopropyl-2-methyl-3-phenylaziridine; (2S,3S)-2-Methyl-1-(1-methylethyl)-3-phenylaziridine; (2S,3S)-3-Phenyl-1-isopropyl-2-methylaziridine; (2S,3S)-1-(1-Methylethyl)-2-methyl-3-phenylaziridine; (2S,3S)-Aziridine, 2-methyl-1-(1-methylethyl)-3-phenyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity grades suitable for research and development as well as process-scale applications. Every batch is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The compound is easily oxidized and light-sensitive; handle and store accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2S,3S)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.