Description

5-Chloro-2-Iodoanisole is a versatile halogenated anisole derivative, a key building block in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the life sciences and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CROs/CMOs serving the global pharmaceutical and chemical industries.

Basic Information

Product Name	5-Chloro-2-Iodoanisole
CAS No.	755027-21-5
Molecular Formula	C7H6ClIO
Molecular Weight	268.48 g/mol
Synonyms	1-Chloro-4-iodo-2-methoxybenzene; 2-Iodo-5-chloroanisole; 5-Chloro-2-iodo-1-methoxybenzene; 2-Methoxy-4-chloroiodobenzene; 4-Chloro-2-iodoanisole; Benzene, 1-chloro-4-iodo-2-methoxy-; (2-Iodo-5-chlorophenyl) methyl ether
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Iodoanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.