Description

4-Fluoro-2-(trifluoromethyl)phenylhydrazine is a specialized aromatic hydrazine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, makes it a valuable precursor for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where the fluorine moiety improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and advanced materials with specific electronic or surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for constructing complex heterocyclic compounds, such as indoles and pyrazoles, via cyclization reactions.
• Dye and Pigment Industry: Potential intermediate in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	4-Fluoro-2-(trifluoromethyl)phenylhydrazine
CAS No.	754973-91-6
Molecular Formula	C7H6F4N2
Molecular Weight	194.13 g/mol
Synonyms	(4-Fluoro-2-(trifluoromethyl)phenyl)hydrazine; 1-(4-Fluoro-2-(trifluoromethyl)phenyl)hydrazine; 4-Fluoro-α,α,α-trifluoro-o-tolylhydrazine; 2-(Trifluoromethyl)-4-fluorophenylhydrazine; 4-Fluoro-2-trifluoromethylphenylhydrazine; Hydrazine, (4-fluoro-2-(trifluoromethyl)phenyl)-; 754973-91-6
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for all our fine chemical intermediates. Production of 4-Fluoro-2-(trifluoromethyl)phenylhydrazine is monitored through in-process controls and finalized with comprehensive analytical testing to ensure batch-to-batch consistency and high purity. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality system supports compliance with relevant standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.