Description

S-Benzyl 2-Aminoethanethioate Hydrochloride is a high-purity, protected cysteine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating complex peptide coupling reactions and protecting sensitive thiol groups during multi-step synthetic processes. It is primarily needed by pharmaceutical R&D teams, peptide chemists, and fine chemical manufacturers developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of cysteine-containing peptides and peptidomimetics for drug discovery programs.
• Peptide Synthesis: Used as a protected cysteine derivative in solid-phase and solution-phase peptide synthesis (SPPS) to prevent unwanted disulfide bond formation.
• Chemical Biology Research: Serves as a tool compound for studying thiol-mediated biochemical pathways and protein modifications.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts that utilize thiol or amine functionalities.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Bioconjugation Chemistry: Acts as a reagent for introducing protected thiol handles onto biomolecules or other synthetic scaffolds.

Basic Information

Product Name	S-Benzyl 2-Aminoethanethioate Hydrochloride
CAS No.	754172-97-9
Molecular Formula	C9H12ClNOS
Molecular Weight	217.71 g/mol
Synonyms	S-Benzyl-L-cysteine hydrochloride; 2-Amino-3-(benzylthio)propanoic acid hydrochloride; (R)-2-Amino-3-(benzylthio)propanoic acid hydrochloride; L-Cysteine, S-benzyl-, hydrochloride; S-Benzylcysteine HCl; S-Bzl-Cys-OH·HCl; N-Acetyl-S-benzylcysteine hydrochloride (related derivative); Amino acid protecting group reagent
EINECS	Contact for details

Quality Control

Our S-Benzyl 2-Aminoethanethioate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.